Publications

J. Abrams and J. Nance (2021). A polarity pathway for exocyst-dependent intracellular tube extension. eLife 10:e65169.

A. Z. A. Schwartz and J. Nance (2020). Stimulating embryo polarization with mitochondrial peroxide. Developmental Cell 53: 261-262.

J. G. Montoyo-Rosario, S. T. Armenti, Y. Zilberman and J. Nance (2020). The role of pkc-3 and genetic suppressors in Caenorhabditis elegans epithelial cell junction formation. Genetics 214: 941-959. 

D. McIntyre and J. Nance (2020).  Niche cell wrapping ensures primordial germ cell quiescence and protection from intercellular cannibalism.  Current Biology 30: 708-714.e.4.

B. Goldstein and J. Nance (2020).  C. elegans gastrulation: a model for understanding how cells polarize, change shape, and journey toward the center of an embryo.  Genetics 214: 265-277.

C. Maniscalco, A.E. Hall, and J. Nance (2019).  An interphase contractile ring reshapes primordial germ cells to allow bulk cytoplasmic remodeling.  The Journal of Cell Biology 219: e201906185.

J. Nance and C. Frøkjær-Jensen (2019).  The Caenorhabditis elegans transgenic toolbox.  Genetics 212: 959-990.

K.B. Beer, J. Rivas-Castillo, K. Kuhn, G. Fazeli, B. Karmann, J.F. Nance, C. Stigloher, and A.M. Wehman (2018).  Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry.PNAS 115: E1127-1136.  

Y. Zilberman, J. Abrams, D. C. Anderson, and J. Nance (2017).  Cdc42 regulates junctional actin but not cell polarization in the Caenorhabditis elegans epidermis.  The Journal of Cell Biology 216: 3729-3744

Y. Abdu, C. Maniscalco, J. M. Huddleston, T. L. Chew, and J. Nance (2016).  Developmentally programmed germ cell remodelling by endodermal cell cannibalism.  Nature Cell Biology 18: 1302-1310.  Highlighted in Nature Cell Biology. Previewed in Developmental Cell.  Current Biology dispatch.  Highlighted in F1000.  

T. Koorman, D. Klompstra, M. van der Voet, J.J. Ramalho, S. Nieuwenhuize, S. van den Heuvel, J. Tavernier, J. Nance, and M. Boxem (2016). A combined binary interaction and phenotypic map of C. elegans cell polarity proteins.  Nature Cell Biology 18: 337-346.

R. Mainpal, J. Nance, and J. L. Yanowitz (2015).  A germ cell determinant reveals parallel pathways for germ line development in Caenorhabditis elegans.  Development 142: 3571-3582.

 D. Klompstra, D. C. Anderson, J. Y. Yeh, Y. Zilberman, and J. Nance (2015).  An instructive role for C. elegans E-cadherin in translating cell contact cues into cortical polarity.  Nature Cell Biology 17: 726-735.  Highlighted in F1000.

 S. T. Armenti, L. L. Lohmer, D. R. Sherwood, and J. Nance (2014).  Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins.  Development 141: 4640-4647.

 J. Nance (2014).  Getting to know your neighbor: cell polarization in early embryos (2014). The Journal of Cell Biology 206: 823-832.

 S. T. Armenti, E. Chan, and J. Nance (2014).  Polarized exocyst-mediated vesicle fusion directs intracellular lumenogenesis within the C. elegans excretory cell.  Developmental Biology 394: 110-121.

 M. Rohrschneider and J. Nance (2013).  The union of somatic gonad precursors and primordial germ cells during Caenorhabditis elegans embryogenesis. Developmental Biology 379: 139-151.  Highlighted in: F1000.

 E. Chan and J. Nance (2013).  Mechanisms of CDC-42 activation during contact-induced cell polarization.  Journal of Cell Science 126: 1692-1702.  Previewed in Journal of Cell Science.

 D. Chihara and J. Nance (2012).  An E-cadherin-mediated hitchhiking mechanism for C. elegans germ cell internalization during gastrulation.  Development 139: 2547-2556. Highlighted in: F100o.

 A. M. Wehman, C. Poggioli, P. Schweinsberg, B. D. Grant, and J. Nance (2011).  The P4 ATPase TAT-5 inhibits the budding of extracellular vesicles in C. elegans embryos.  Current Biology 21: 1951-1959.  Highlighted in F1000, Current Biology dispatch.

 J. Nance and J. Zallen (2011).  Elaborating polarity: PAR proteins and the cytoskeleton.  Development 138: 799-809.

 A. Achilleos, A. M. Wehman and J. Nance (2010). PAR-3 mediates the initial clustering and apical localization of junction and polarity proteins during C. elegans intestinal epithelial cell polarization. Development 137: 1833-1842. Highlighted in: F1000.

 M. R. Rohrschneider and J. Nance (2009). Polarity and cell fate specification in the control of C. elegans gastrulation.  Developmental Dynamics 238: 789-796.  Highlighted in: F1000.

 D. C. Anderson, J. S. Gill*, R. M. Cinalli*, and J. Nance (2008). Polarization of the C. elegans embryo by RhoGAP-mediated exclusion of PAR-6 from cell contacts. Science 320: 1771-1774.  Highlighted in: F1000,Cell Leading EdgeScience Signaling Editor’s ChoiceNature Reviews Molecular Cell Biology Research Highlight.

 R. Totong, A. Achilleos, and J. Nance (2007). PAR-6 is required for junction formation but not apicobasal polarization in C. elegans embryonic epithelial cells. Development 134: 1259-1268.  Highlighted in: F1000.